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	<title>PharmExec Blog</title>
	<link>http://blog.pharmexec.com</link>
	<description>The Business of Pharmaceuticals</description>
	<pubDate>Tue, 13 May 2008 17:05:05 +0000</pubDate>
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		<itunes:summary>The Business of Pharmaceuticals</itunes:summary>
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			<title>PharmExec Blog</title>
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		<title>The DTC Hearings: Gleaning Some Nuggets</title>
		<link>http://blog.pharmexec.com/2008/05/13/the-dtc-hearings-gleaning-some-nuggets/</link>
		<comments>http://blog.pharmexec.com/2008/05/13/the-dtc-hearings-gleaning-some-nuggets/#comments</comments>
		<pubDate>Tue, 13 May 2008 17:05:05 +0000</pubDate>
		<dc:creator>Patrick Clinton</dc:creator>
		
		<category><![CDATA[Advertising]]></category>

		<guid isPermaLink="false">http://blog.pharmexec.com/2008/05/13/the-dtc-hearings-gleaning-some-nuggets/</guid>
		<description><![CDATA[Last week’s congressional hearings on direct-to-consumer advertising were, as expected, pretty inconclusive—but that doesn’t mean we won’t be hearing a lot more on the topic. The big question, I think, is when (and whether) the debate will ever get to the point of realism about what DTC is and can be. The idea of advertising [...]]]></description>
			<content:encoded><![CDATA[<p>Last week’s <a href="http://energycommerce.house.gov/cmte_mtgs/110-oi-hrg.050808.DTC.shtml" target="_blank">congressional hearings on direct-to-consumer advertising</a> were, as expected, pretty inconclusive—but that doesn’t mean we won’t be hearing a lot more on the topic. The big question, I think, is when (and whether) the debate will ever get to the point of realism about what DTC is and can be. The idea of advertising as serious, balanced education about a condition and its treatments is mostly absurd, though some individual campaigns have achieved striking success. The idea that risks and benefits should somehow represent a fifty-fifty mixture makes no sense—unless you’re trying to guarantee that patients avoid the drug entirely (as some critics clearly wish).</p>
<p>Perhaps the most sophisticated critique is that drugs shouldn&#8217;t be widely promoted until they&#8217;ve been on the market long enough to ensure that risks are understood. But there&#8217;s a big question there too:  Can we truly discover useful information about real-world risks without exposing patients to risk?</p>
<p>Ads should be accurate, but in the long run the real issue is whether they drive appropriate or inappropriate prescribing. And despite the analysis DTC has been subjected to, that’s apparently not yet known, or even likely to be known.</p>
<p>In the meantime, one of the great pleasures of grubbing through congressional testimony is the discovery of fascinating, quotable tidbits. Here are a few from the DTC hearing: <a href="http://blog.pharmexec.com/2008/05/13/the-dtc-hearings-gleaning-some-nuggets/#more-128" class="more-link">(more&#8230;)</a></p>
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		<item>
		<title>Scientists Without Borders</title>
		<link>http://blog.pharmexec.com/2008/05/13/scientists-without-borders/</link>
		<comments>http://blog.pharmexec.com/2008/05/13/scientists-without-borders/#comments</comments>
		<pubDate>Tue, 13 May 2008 16:04:23 +0000</pubDate>
		<dc:creator>Joanna Breitstein</dc:creator>
		
		<category><![CDATA[R&amp;D]]></category>

		<category><![CDATA[Strategy]]></category>

		<category><![CDATA[Technology]]></category>

		<guid isPermaLink="false">http://blog.pharmexec.com/2008/05/13/scientists-without-borders/</guid>
		<description><![CDATA[The New York Academy of Sciences held its kickoff last night of Scientists Without Borders. “It’s a Match.com for organizations and resources focused on helping the developing world,&#8221; said NYAS president Ellis Rubinstein.
The initiative so far consists of a just-launched wiki—and, as such, leaves a little to be desired in terms of content. But the [...]]]></description>
			<content:encoded><![CDATA[<p>The New York Academy of Sciences held its kickoff last night of <a href="http://scientistswithoutborders.nyas.org/">Scientists Without Borders</a>. “It’s a Match.com for organizations and resources focused on helping the developing world,&#8221; said NYAS president Ellis Rubinstein.</p>
<p>The initiative so far consists of a just-launched wiki—and, as such, leaves a little to be desired in terms of content. But the tools are all there, explained the site’s developer, urging everyone in the audience who had resource supplies or demands to sign up, make connections, and work toward new solutions for dire problems such as poverty, disease, hunger, and climate change in sub-Saharan Africa and other places. <a href="http://blog.pharmexec.com/2008/05/13/scientists-without-borders/#more-124" class="more-link">(more&#8230;)</a></p>
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		<item>
		<title>Valeant to Lay Off Half Its Workforce</title>
		<link>http://blog.pharmexec.com/2008/05/06/valeant-to-lay-off-half-its-workforce/</link>
		<comments>http://blog.pharmexec.com/2008/05/06/valeant-to-lay-off-half-its-workforce/#comments</comments>
		<pubDate>Tue, 06 May 2008 13:42:06 +0000</pubDate>
		<dc:creator>Patrick Clinton</dc:creator>
		
		<category><![CDATA[Strategy]]></category>

		<category><![CDATA[Valeant]]></category>

		<guid isPermaLink="false">http://blog.pharmexec.com/2008/05/06/valeant-to-lay-off-half-its-workforce/</guid>
		<description><![CDATA[The last time Pharm Exec covered Valeant Pharmaceuticals, it was in 2005, and things were looking good for the company. It had a new name, and a sleek new organization, lighter than the old by 8,000 employees. New CEO Timothy Tyson had created a talented and enthusiastic new management team. A new strategy was in [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://blog.pharmexec.com/wp-content/uploads/2008/05/110105_pe_cvr_7633.jpg" title="Timothy Tyson"><img src="http://blog.pharmexec.com/wp-content/uploads/2008/05/110105_pe_cvr_7633.thumbnail.jpg" alt="Timothy Tyson" align="right" /></a>The last time <em>Pharm Exec</em> covered <a href="http://pharmexec.findpharma.com/pharmexec/article/articleDetail.jsp?id=197794&amp;pageID=1&amp;sk=&amp;date=" target="_blank">Valeant Pharmaceuticals,</a> it was in 2005, and things were looking good for the company. It had a new name, and a sleek new organization, lighter than the old by 8,000 employees. New CEO Timothy Tyson had created a talented and enthusiastic new management team. A new strategy was in place. And Viramidine, a replacement drug for Valeant&#8217;s hepatitis-C treatment, ribavirin (marketed by Schering-Plough under the name Rebetol), seemed just around the corner.</p>
<p>Late last week, the company announced that it was <a href="http://www.latimes.com/business/la-fi-valeant3-2008may03,0,5741809.story" target="_blank">laying off roughly half of its workforce.</a> Tyson is gone. And Viramidine, now known as Taribavirin is, well, just around the corner. What went wrong? <a href="http://blog.pharmexec.com/2008/05/06/valeant-to-lay-off-half-its-workforce/#more-122" class="more-link">(more&#8230;)</a></p>
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		<item>
		<title>Merck&#8217;s Cordaptive: A Nasty Surprise</title>
		<link>http://blog.pharmexec.com/2008/05/01/mercks-cordaptive-a-nasty-surprise/</link>
		<comments>http://blog.pharmexec.com/2008/05/01/mercks-cordaptive-a-nasty-surprise/#comments</comments>
		<pubDate>Thu, 01 May 2008 15:22:05 +0000</pubDate>
		<dc:creator>Walter Armstrong</dc:creator>
		
		<category><![CDATA[Regulatory]]></category>

		<category><![CDATA[People]]></category>

		<category><![CDATA[R&amp;D]]></category>

		<category><![CDATA[News Media]]></category>

		<guid isPermaLink="false">http://blog.pharmexec.com/2008/05/01/mercks-cordaptive-a-nasty-surprise/</guid>
		<description><![CDATA[If there’s one piece of pharma news that should come as no surprise, it’s FDA throwing a new drug back at its maker with a “Try again later.” After all, the agency spent last year handing out “approvable” letters like pharma hands out freebies. That’s why  we’re  surprised that analysts, reporters, and possibly [...]]]></description>
			<content:encoded><![CDATA[<p><a href="http://blog.pharmexec.com/wp-content/uploads/2008/05/images-11.jpg" title="images-11.jpg"><img src="http://blog.pharmexec.com/wp-content/uploads/2008/05/images-11.thumbnail.jpg" alt="images-11.jpg" align="right" /></a>If there’s one piece of pharma news that should come as no surprise, it’s FDA throwing a new drug back at its maker with a “Try again later.” After all, the agency spent last year handing out “approvable” letters like pharma hands out freebies. That’s why  <em>we’re  </em>surprised that analysts, reporters, and possibly even Merck R&amp;D superstar Peter Kim (right) were all thrown for a  loop at the knockdown of Cordaptive, the company’s biggest ’08 contender.</p>
<p> <a href="http://blog.pharmexec.com/2008/05/01/mercks-cordaptive-a-nasty-surprise/#more-118" class="more-link">(more&#8230;)</a></p>
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		<item>
		<title>Millennium Founder Heads a New Biotech</title>
		<link>http://blog.pharmexec.com/2008/04/29/millennium-founder-heads-a-new-biotech/</link>
		<comments>http://blog.pharmexec.com/2008/04/29/millennium-founder-heads-a-new-biotech/#comments</comments>
		<pubDate>Tue, 29 Apr 2008 18:49:15 +0000</pubDate>
		<dc:creator>Patrick Clinton</dc:creator>
		
		<category><![CDATA[People]]></category>

		<category><![CDATA[Deals]]></category>

		<category><![CDATA[Biotech]]></category>

		<guid isPermaLink="false">http://blog.pharmexec.com/2008/04/29/millennium-founder-heads-a-new-biotech/</guid>
		<description><![CDATA[If, in the wake of the sale of Millennium, you&#8217;ve been wondering what ever happened to the company&#8217;s co-founder and longtime CEO Mark Levin, the answer was in this morning&#8217;s deal news, in the announcement that a young biotech called Constellation Pharmaceuticals had closed a $32 million Series A financing. The companies coming up with [...]]]></description>
			<content:encoded><![CDATA[<p align="left"><a href="http://blog.pharmexec.com/wp-content/uploads/2008/04/mark-levin.png" title="Mark Levin"><img src="http://blog.pharmexec.com/wp-content/uploads/2008/04/mark-levin.thumbnail.png" alt="Mark Levin" align="right" /></a>If, in the wake of the <a href="http://www.marketintelligencecenter.com/articles/581509" target="_blank">sale of Millennium,</a> you&#8217;ve been wondering what ever happened to the company&#8217;s co-founder and longtime CEO Mark Levin, the answer was in this morning&#8217;s deal news, in the <a href="http://biz.yahoo.com/bw/080429/20080429005326.html?.v=1" target="_blank">announcement</a> that a young biotech called Constellation Pharmaceuticals had closed a $32 million Series A financing. The companies coming up with the funding: The Column Group, Venrock, and Third Rock Ventures—a company whose <a href="http://blog.pharmexec.com/wp-admin/www.thirdrockventures.com/%20teambios.htm" target="_blank">partner list </a>reads like a Who&#8217;s Who of former Millennium folks—including Mark Levin. <a href="http://blog.pharmexec.com/2008/04/29/millennium-founder-heads-a-new-biotech/#more-117" class="more-link">(more&#8230;)</a></p>
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		<item>
		<title>Microsoft Launches New Tool Kit; Chats About Vista</title>
		<link>http://blog.pharmexec.com/2008/04/24/microsoft-launches-new-tool-kit-chats-about-vista/</link>
		<comments>http://blog.pharmexec.com/2008/04/24/microsoft-launches-new-tool-kit-chats-about-vista/#comments</comments>
		<pubDate>Thu, 24 Apr 2008 15:05:35 +0000</pubDate>
		<dc:creator>George Koroneos</dc:creator>
		
		<category><![CDATA[Technology]]></category>

		<category><![CDATA[Events]]></category>

		<guid isPermaLink="false">http://blog.pharmexec.com/2008/04/24/microsoft-launches-new-tool-kit-chats-about-vista/</guid>
		<description><![CDATA[Microsoft is at the tail end of its Microsoft Health and Life Sciences Developer and Solutions Conference in Atlantic City. Pharm Exec couldn&#8217;t make the show, but Bill Gate&#8217;s life sciences crew was nice enough to give us a call and fill us in on the launch of its new development tool kit and how [...]]]></description>
			<content:encoded><![CDATA[<p><img src="http://blog.pharmexec.com/wp-content/uploads/2008/04/mslogo-1.thumbnail.jpg" alt="Microsoft" align="right" />Microsoft is at the tail end of its <a href="http://www.microsoft.com/presspass/press/2008/apr08/04-21MHLSDevConMA.mspx" target="_blank">Microsoft Health and Life Sciences Developer and Solutions Conference</a> in Atlantic City. <em>Pharm Exec</em> couldn&#8217;t make the show, but Bill Gate&#8217;s life sciences crew was nice enough to give us a call and fill us in on the launch of its new development tool kit and how quickly pharma is adopting Vista.</p>
<p>The big news out of AC is the release of Microsoft&#8217;s <a href="http://office.microsoft.com/en-us/products/FX102204261033.aspx" target="_blank">Office for Business Applications</a> (OBA) for the life sciences industry. This set of tools allows software developers to build applications that seamlessly connect back-end enterprise systems with MS Office program.   <a href="http://blog.pharmexec.com/2008/04/24/microsoft-launches-new-tool-kit-chats-about-vista/#more-113" class="more-link">(more&#8230;)</a></p>
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		<item>
		<title>Times&#8217; Drug-Supply Snoops Bag a Pulitzer</title>
		<link>http://blog.pharmexec.com/2008/04/09/times-drug-supply-snoops-bag-a-pulitizer/</link>
		<comments>http://blog.pharmexec.com/2008/04/09/times-drug-supply-snoops-bag-a-pulitizer/#comments</comments>
		<pubDate>Wed, 09 Apr 2008 18:34:16 +0000</pubDate>
		<dc:creator>Walter Armstrong</dc:creator>
		
		<category><![CDATA[Regulatory]]></category>

		<category><![CDATA[Safety]]></category>

		<category><![CDATA[News Media]]></category>

		<category><![CDATA[Manufacturing]]></category>

		<category><![CDATA[Supply Chain]]></category>

		<guid isPermaLink="false">http://blog.pharmexec.com/2008/04/09/times-drug-supply-snoops-bag-a-pulitizer/</guid>
		<description><![CDATA[The New York Times likes to give the drug industry a hard time with its (unbranded) scandal of the week series—off-label promoting, suppressing data, that sort of thing. But when the 2008 Pulitzer Prizes were handed out on Monday, the winner for best investigative reporting was a series by the Times that even its harshest [...]]]></description>
			<content:encoded><![CDATA[<p><img src="http://blog.pharmexec.com/wp-content/uploads/2008/04/images.thumbnail.jpg" alt="New York Times" align="right" /><em>The New York Times</em> likes to give the drug industry a hard time with its (unbranded) scandal of the week series—off-label promoting, suppressing data, that sort of thing. But when the 2008 Pulitzer Prizes were handed out on Monday, the winner for best investigative reporting was a series by the <em>Times </em>that even its harshest pharma critics have to appreciate.</p>
<p>Called “The Toxic Pipeline,” the series is a truly groundbreaking investigation into the counterfeit, adulterated, and dangerous drugs that are made in China and sold to an unsuspecting world. Reporters Walt Bogdanich and Jake Hooker spent the better part of the past year tracking the drug industry’s global supply chain across four continents to locate its faulty links where no regulation of corrupt officials facilitate a crisis level of contamination.   <a href="http://blog.pharmexec.com/2008/04/09/times-drug-supply-snoops-bag-a-pulitizer/#more-111" class="more-link">(more&#8230;)</a></p>
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		<item>
		<title>PRSA Day 2: Join the Conversation</title>
		<link>http://blog.pharmexec.com/2008/04/04/prsa-day-2-join-the-conversation/</link>
		<comments>http://blog.pharmexec.com/2008/04/04/prsa-day-2-join-the-conversation/#comments</comments>
		<pubDate>Fri, 04 Apr 2008 17:30:43 +0000</pubDate>
		<dc:creator>Joanna Breitstein</dc:creator>
		
		<category><![CDATA[Meetings]]></category>

		<category><![CDATA[Marketing]]></category>

		<category><![CDATA[E-Media]]></category>

		<guid isPermaLink="false">http://blog.pharmexec.com/2008/04/04/prsa-day-2-join-the-conversation/</guid>
		<description><![CDATA[The second dispatch from Marina Maher Communication&#8217;s healthcare guru Megan Svensen:
It’s the second day of the 19th Annual PRSA Health Academy meeting in Chicago and the morning has provided more valuable learnings.  Ed Schipul, CEO of Schipul – The Web Marketing Company, gave a great analogy in his talk: He says joining the blogosphere [...]]]></description>
			<content:encoded><![CDATA[<p><em>The second dispatch from <a href="http://www.mahercomm.com/">Marina Maher Communication</a>&#8217;s healthcare guru Megan Svensen:</em></p>
<p align="left"><a href="http://blog.pharmexec.com/wp-content/uploads/2008/04/megan.jpg" title="Megan Svenson"><img src="http://blog.pharmexec.com/wp-content/uploads/2008/04/megan.thumbnail.jpg" alt="Megan Svenson" align="left" height="168" width="115" /></a>It’s the second day of the 19th Annual <a href="http://www.prsa.org/">PRSA</a> Health Academy meeting in Chicago and the morning has provided more valuable learnings.  Ed Schipul, CEO of <a href="http://www.schipul.com/">Schipul – The Web Marketing Company</a>, gave a great analogy in his talk: He says joining the blogosphere after a crisis is like saying “I didn’t kill him” as you stand over a dead body. And working in pharma, we know, eventually, there will be a crisis.</p>
<p align="left">I’ve been having quite a few conversations with my pharma clients and friends about how best to join the conversation.  Many of us are doing that through vehicles that allow us more control (and therefore less risk) over the content – like podcasts and e-newsletters. <a href="http://blog.pharmexec.com/2008/04/04/prsa-day-2-join-the-conversation/#more-107" class="more-link">(more&#8230;)</a></p>
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		<title>PRSA Day 1: Talking&#8217; Cross Gen</title>
		<link>http://blog.pharmexec.com/2008/04/04/prsa-day-1-talking-cross-gen/</link>
		<comments>http://blog.pharmexec.com/2008/04/04/prsa-day-1-talking-cross-gen/#comments</comments>
		<pubDate>Fri, 04 Apr 2008 14:02:56 +0000</pubDate>
		<dc:creator>Joanna Breitstein</dc:creator>
		
		<category><![CDATA[Meetings]]></category>

		<category><![CDATA[Marketing]]></category>

		<category><![CDATA[News Media]]></category>

		<guid isPermaLink="false">http://blog.pharmexec.com/2008/04/04/prsa-day-1-talking-cross-gen/</guid>
		<description><![CDATA[The discussions over the next model for pharma fall all over the map, but include one central component: a conversation with consumers. How to do it? Here, Megan Svensen, executive vice president of healthcare for Marina Maher Communications, reports in from the annual Public Relations Society of America boot camp on healthcare.
I&#8217;m coming to you [...]]]></description>
			<content:encoded><![CDATA[<p><img src="http://blog.pharmexec.com/wp-content/uploads/2008/04/prsa.thumbnail.png" alt="PRSA" align="right" /><em>The discussions over the next model for pharma fall all over the map, but include one central component: a conversation with consumers. How to do it? Here, Megan Svensen, executive vice president of healthcare for Marina Maher Communications, reports in from the annual Public Relations Society of America boot camp on healthcare.</em></p>
<p>I&#8217;m coming to you from the 19th Annual PRSA Health Academy meeting in Chicago. The topic this year is Health Care Communications Strategy: Boomers, Xers and Nexters&#8230;Communicating in a Cross-Generational/Cross-Cultural Landscape. The day began with a talk by Jane Brody, the &#8220;holy grail&#8221; of health columnists. She started off by talking about how we as PR communicators are vital to the health of the nation. I must say, it was nice of someone to notice.</p>
<p>Among her topics she talked about the need for compliance—the &#8220;holy grail&#8221; of pharma execs everywhere—and how we need to do a better job communicating why consumers should stay on treatment. It was the one message about how to lower our country&#8217;s healthcare costs that may be palatable to conservative industry colleagues. <a href="http://blog.pharmexec.com/2008/04/04/prsa-day-1-talking-cross-gen/#more-105" class="more-link">(more&#8230;)</a></p>
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		<title>ACC News Echoes Cost/Benefit Concerns</title>
		<link>http://blog.pharmexec.com/2008/03/31/acc-news-echoes-costbenefit-concerns/</link>
		<comments>http://blog.pharmexec.com/2008/03/31/acc-news-echoes-costbenefit-concerns/#comments</comments>
		<pubDate>Mon, 31 Mar 2008 16:03:07 +0000</pubDate>
		<dc:creator>Joanna Breitstein</dc:creator>
		
		<category><![CDATA[Regulatory]]></category>

		<category><![CDATA[R&amp;D]]></category>

		<category><![CDATA[Meetings]]></category>

		<guid isPermaLink="false">http://blog.pharmexec.com/2008/03/31/acc-news-echoes-costbenefit-concerns/</guid>
		<description><![CDATA[News flowing from the American College of Cardiology meeting has been dominated by Vytorin. And after the presentation analyzing results yesterday, Miller Tabak analyst Les Fundleyter says, “We’re done for the conference in terms of the important stuff. Vytorin is the story this year.”
So what is Vytorin’s story exactly? Industry watchers say they are still [...]]]></description>
			<content:encoded><![CDATA[<p><img src="http://blog.pharmexec.com/wp-content/uploads/2008/03/accu.thumbnail.png" alt="accu.png" align="right" />News flowing from the <a href="http://www.acc.org/" target="_blank">American College of Cardiology</a> meeting has been dominated by Vytorin. And after the presentation analyzing results yesterday, Miller Tabak analyst Les Fundleyter says, “We’re done for the conference in terms of the important stuff. Vytorin is the story this year.”</p>
<p>So what is Vytorin’s story exactly? Industry watchers say they are still searching for answers, but expect docs to move away from prescribing the drug. Filling in the blanks is the familiar debate over Vytorin’s cost/benefit ratio and the question: Does new necessarily mean better? <a href="http://blog.pharmexec.com/2008/03/31/acc-news-echoes-costbenefit-concerns/#more-103" class="more-link">(more&#8230;)</a></p>
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